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Gout is a rheumatic disease resulting from deposition of uric acid crystals in tissues and fluids within the body. This process is caused by an overproduction or under excretion of uric acid.
Acute gout will typically manifest itself as an acutely red, hot, and swollen joint with excruciating pain. These acute gouty flare-ups respond well to treatment with oral anti-inflammatory medicines and may be prevented with medication and diet changes. Recurrent bouts of acute gout can lead to a degenerative form of chronic arthritis called gouty arthritis.
Gout is a common form of inflammatory arthritis, and is the most common inflammatory arthritis among men. Gout may stick around for long periods, followed by flares for days to weeks, or can become chronic.
Gout is a chronic disease caused by an uncontrolled metabolic disorder, hyperuricemia, which leads to the deposition of monosodium urate crystals in tissue. Hyperuricemia means too much uric acid in the blood. Uric acid is a metabolic product resulting from the metabolism of purines (found in many foods)
A few reasons for gout include being overweight or obese, having hypertension, alcohol intake (beer and spirits more than wine), diuretic use, and a diet rich in meat and seafood.
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Chronic gout is characterized by chronic arthritis, with soreness and aching of joints and may also get tophi (lumps of urate crystals deposited in soft tissue)—usually in cooler areas of the body (Toe, ankle, finger, ear). Gout is also associated with an increased risk of kidney stones.
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